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It was initially shown that in drug addicts, who were accidentally exposed to MPTP, there was a depletion of pigmented nerve cells in the substantia nigra, accompanied by astrogliosis and clustering of microgliosis around nerve cells [41], thus presenting some PD-like features

Shalita et al 41 found that patients with inflammatory acne showed significant improvement in acne severity and appearance when a combination of nicotinamide, azelaic acid, pyridoxine, copper, and folic acid was added to existing acne regimens at both four and eight week follow up

Neuroprotection and braingut axis: evaluated in TBI, encephalopathy and serotonergic/dopaminergic dysfunction models, with neurobehavioral and histological protection reported [2]

Williams, O

Kimatu et al