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Interestingly, monomer 2-Pyr- BF3a was weakly emissive in diluted solutions, but increased its PLQY in the crystalline solid

In rat models of PD, IN DFO has been reported to protect dopaminergic neurons in the substantia nigra and ameliorate motor deficits, suggesting IN DFO reaches the midbrain regions at pharmacologically active concentrations (Febbraro et al., 2013)