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Biochemistry 39:1300513011 Mysona B, Dun Y, Duplantier J, Ganapathy V, Smith SB (2009) Effects of hyperglycaemia and oxidative stress on the glutamate transporters GLAST and system xc in mouse retinal Mller glial cells

Moreover, multiple in vitro (Reference Hseu, Lo and Korivi64,Reference Ko, Kim and Ahn65) and in vivo (Reference Salama and Omar66,Reference Dare, Channa and Nadar67) studies suggest that ergothioneine activates the transcription factor nuclear factor erythroid 2-related factor 2 (Nrf2), which triggers the cellular antioxidant defence system