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MSCs primarily engage in immunomodulatory activities through cell-to-cell interactions with immune cells, including T cells, B cells, natural killer (NK) cells, macrophages, monocytes, dendritic cells (DCs), and neutrophils (252)

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Zhang Y, Xu Y, Zhang L, Chen Y, Wu T, Liu R, Sui W, Zhu Q, Zhang M (2022) Licorice extract ameliorates hyperglycemia through reshaping gut microbiota structure and inhibiting TLR4/NF-B signaling pathway in type 2 diabetic mice

Originally investigated by researchers for its profound cytoprotective effects on the gastrointestinal mucosaspecifically in the healing of gastric ulcers and inflammatory bowel diseasethe therapeutic potential of BPC-157 has since expanded dramatically into the realms of severe musculoskeletal repair, soft tissue regeneration, and advanced neuroprotection

Targeting the USP7-PRMT6 epigenetic axis overcomes chemoresistance in breast cancer by coordinating H3R2me2a deposition and RNF168 methylation for DNA repair and ferroptosis blockade