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In parallel, LPS downregulated the OXPHOS cycle and triggered the accumulation of succinate, which contributed to the stabilization of HIF1 andvia succinate oxidation by mitochondrial succinate dehydrogenaseto the production of mitochondrial ROS and subsequent pro-inflammatory gene expression with enhanced production of IL-1 (Mills et al., 2016)

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This puts your body into ketosis, releasing three essential ketones: acetoacetate, beta-hydroxybutyrate (BHB), and acetone for energy

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