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Existing literature on the anti-CRC effects of HT suggests that HT promotes intracellular ROS generation in HCT116 and SW620 cells through the inhibition of TrxR1, a downstream target of Nrf2, leading to the inhibition of cell growth 11

Chavakis, T., Mitroulis, I

J Biol Chem 2010;285:276018

(2015) Dietary Vitamin D and Its Metabolites Non-Genomically Stabilize the Endothelium PLoS ONE

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