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Description

During extracellular-matrix separation, receptor-interacting protein kinase 1 (RIPK1) triggers mitochondrial autophagy via a pathway reliant on the mitochondrial phosphatase PGAM5, which regulates mitochondrial dynamics to influence cellular senescence (Hawk et al

2017;14(Supplement_5):S35762

Shore, N

These patients represent a very small proportion of the population (approximately 1 of 200,000 individuals in the world) and have very severe hyperhomocysteinemia that can reach 400 mol/L