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The bulk metals are chemically soft and preferentially interact strongly with soft inhibitor species

V.ElumogoN.et al

COX2 is an enzyme that plays an important role in the synthesis of prostaglandins involved in inflammatory responses (225)

In 2000, the prevalence was reported as 1 in 150 children, which progressively decreased to 1 in 125 in 2004, 1 in 110 in 2006, 1 in 88 in 2008, 1 in 68 in 2010 and 2012, 1 in 59 in 2014an 2018, and 1 in 36 in 2023 in the U.S

In the present study, we aimed to investigate the modulatory effects of SFN in imiquimod (IMQ)-induced psoriatic mice, as well as the underlying molecular mechanisms