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Moreover, AS-IV can interfere with the influence of TGF-1 stimulation on the incorporation of [3H]proline in HSCs, as demonstrated by the decreased incorporation amount and inhibition of TGF-1-induced proliferation and collagen synthesis in HSCs, thereby alleviating PS-induced immune hepatic fibrosis (Fig

Ding H, Cui Y, Yang J, Li Y, Zhang H, Ju S, Ren X, Ding C, Zhao J

To overcome these limitations, the modification of boundary conditions and parameters in drug metabolism based on actual measurements may lead to better prediction

Belova, O

[DOI] [PubMed] [Google Scholar] 198.Zhao Z., Lange D.J., Voustianiouk A., MacGrogan D., Ho L., Suh J., Humala N., Thiyagarajan M., Wang J., Pasinetti G.M