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We also showed by ChIP-qPCR that during LEC2-induced SE formation, SUVH1-6Myc was enriched at the CHH hypermethylated regions of totipotency-regulating genes, including the embryonic regulators ( LEC1 , ABI3 , FUS3 , and BBM ), auxin biosynthesis genes ( YUC1 , YUC5 , and YUC10 ), and fatty acid biosynthesis gene ( KASI ) (Fig