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Differential expression analysis was conducted using pyDESeq2 (ref

Selected environmental factors were analyzed by canonical correspondence analysis (CCA) and redundancy analysis (RDA)

Manganese modulation of MAPK pathways: effects on upstream mitogen activated protein kinase kinases and mitogen activated kinase phosphatase-1 in microglial cells

Particularly, exercise can strengthen cerebral blood flow, boosting the supply of oxygen and nutrients to the brain, thus facilitating neuronal function and survival (Liang et al., 2021)