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In our study, as the intracellular -GC level was only increased slightly compared with that of original strain W303-1b when F pathway was introduced, we artificially introduced a flexible six-glycine linker between the two enzymes of G pathway as well as P pathway to improve the coupling efficiency by mimicking the native domain fusion of GshF

Poly (ADP-Ribose) polymerase (PARP) inhibitors: Exploiting a synthetic lethal strategy in the clinic

Omega-3s are also present in walnuts and flax seeds

Although clinical translation of HAT inhibitors in glioblastoma is still in its early stages, accumulating evidence underscores their therapeutic potential, either as monotherapies or in rational combination regimens

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