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The use of various density gradient techniques for the enrichment of motile sperm media has therefore been investigated and this application sheet presents some of the recommended methods

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Ethics declarations Competing interests LM, VR and GK are listed as inventors of a patent that protects the use of cysteamine for CF treatment

Kaplowitz [43] reported angiotensin-converting enzyme [ACE] inhibitors, amoxicillin, chlorpromazine, erythromycins and sulindac to be associated with etiology of cholestasis