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"I'd say maybe only a handful of people at most in the last 10 years have I ever actually thought would benefit from B12 injections." As to why some physicians would be needlessly prescribing B12 shots, he said, "It may be just habit

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Second, in septic shock, obese patients may receive suboptimal exposure to AVP with conventional dosing strategies due to its rapid distribution into extracellular fluid, and volume of distribution being affected by weight-based fluid resuscitation and increased adipose tissue [36, 37]