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Nature Biotechnology 40(11):1624-1633, 2022

409 In addition to genomic markers, functional indicators of autophagy flux, such as LC3 puncta, p62/SQSTM1 accumulation, and ATG expression, are under investigation as clinical biomarkers

Sirtuin 2 (SIRT2)-P53 signaling pathway The SIRT2-p53 pathway exerts neuroprotective effects by modulating GPX4 and SCL7A11, inhibiting the occurrence of ferroptosis (100)