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2017;8: e2716

The incidence of HCC in BSV users (n=6, 4.4 per 1000 person-years [PYs]) was similar to that in TAF users (8.5 per 1000 PYs, log-rank P =0.111, HR 2.098, 95% confidence interval [CI] 0.8275.324), however, significantly lower than those in ETV (n=38, 12.7 per 1000 PYs, log-rank P =0.026, HR 2.603, 95% CI 1.0876.233) and TDF users (12.7 per 1000PYs, log-rank P =0.035, HR 2.539, 95% CI 1.0346.234)

The gut microbiome comes into play here in making sure that the metabolites are excreted and not reabsorbed

doi:10.1001/archinte.1931.00140200095007

Cap or vial colours may vary depending on batch availability, but this does not affect the quality, purity, or integrity of the product