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Approximate H chain amino acid residues are 455 and MW is ~50 kDa

The accumulation of lipid peroxides leads to oxidative damage of cell membranes, disrupting their structural and functional integrity, and serves as an important initiating step in promoting ICD

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Serritelli E, Sartini D, Campagna R, Pozzi V, Martin N, van Haren M, Salvolini E, Cecati M, Rubini C, Emanuelli M (2024) Targeting nicotinamide N-methyltransferase decreased aggressiveness of osteosarcoma cells