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19,24 This latter function of TRIF signaling involves activation of an E3 ubiquitin ligase, Peli1, which conjugates lysine 63-linked ubiquitin chains to RIP1, thereby facilitating the recruitment and activation of IKK

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Teng MW, Bowman EP, McElwee JJ, Smyth MJ, Casanova JL, Cooper AM et al

The nanoparticles were prepared via a modified phase-inversion and layer-by-layer method, with BoxBehnken design assessing formulation variables