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Description

The mice that were neonatally immunized did not show those pathological changes

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The nuclei were bound to activated Concanavalin beads and incubated with the primary antibody (1:100, DO-1, Santa Cruz Biotechnology, Dallas, United States) or isotype control overnight at 4 C

More recently, spinocerebellar ataxia type 2 has also been linked to the presence of a transition polymorphism in the GSTO2 gene (rs2297235 A183G) which significantly correlates with the age at disease onset