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Svensson RU, Parker SJ, Eichner LJ, et al

This study revealed that higher ASC in ripening orange was associated with an augmented expression of four genes involved in ASC biosynthesis, encoding GDP-d-mannose-3,5-epimerase (EC 5.1.3.18), GDP-l-galactose-phosphorylase (EC 2.7.7.69), l-galactose dehydrogenase (EC 1.1.1.316) and l-galactono-1,4-lactone dehydrogenase (EC 1.3.2.3), together with attenuated activities of ASC oxidase and ASC peroxidase, which are involved in ASC degradation