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Zhang Y, Li M, Gao X et al (2019) Nanotechnology in cancer diagnosis: Progress, challenges and opportunities

Zileuton, an FDA-approved oral medication for treating asthma, is an ALOX5 inhibitor that exerts neuroprotective effects by blocking ALOX5-mediated glutamate toxicity and ferroptosis in HT22 cells, a mouse hippocampal cell line [301]