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3,5-diCQA increased the content of melanin in melanocytes in a dose-dependent manner, the possible mechanism is that 3,5-diCQA promoted the phosphorylation of Akt and GSK-3 , leading to the accumulation of - Catenin in the cytoplasm

Data processing Protein abundance was calculated as a ratio of Gclc / vs

The groups receiving uncross-linked PVA or EBPBA solution showed no significant difference relative to the NC group, emphasizing the importance of phenylboronic ester bonds for scavenging ROS

All statistical analyses were performed using STATISTICA for Windows version 8.0 software (StatSoft Inc, Tulsa, OK, USA)

10.1021/tx0501738 Chem