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Persistent severe symptoms that interfere with daily activities or lead to dehydration should prompt immediate medical consultation, as medication discontinuation or alternative treatments may be necessary

Proper laser settings, wavelength selection, and technique are critical to achieving results while minimizing risks

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Furthermore, the observed role of the oxidative pentose phosphate pathway in regulating NADPH-dependent antioxidant balance during MPLA treatment suggests a potential contribution to protection against infection-induced organ injury

GO pathway analysis of sensitized-specific hypo-DMRs showed enrichment in immune response and cell-cell adhesion-related pathways (Fig