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These include studies of Methyl-B12, folinic acid, and trimethylglycine (TMG) [6, 7, 26], high dose folinic acid [27, 28], high dose vitamin B6 with magnesium [29], vitamin D [30,31,32], high-dose carnitine [33, 34], CoQ10 [35], and high-dose Vitamin C [13, 36]

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