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Of particular relevance, the ECM not only provides structural support and mechanical integrity through components like HA but also actively participates in regulating cellular processes such as growth, differentiation, and dynamic remodeling [125, 126]

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Selenium can be converted from inorganic selenium to volatile selenium compounds through the process of cysteine uptake, which is dependent on the xc-cystine-glutamate reverse transport protein, thereby facilitating selenium absorption and the biosynthesis of selenocysteine [141]

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