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Description

Mutagenesis 33(2):179193

Circulating acylcarnitine profile in human heart failure: a surrogate of fatty acid metabolic dysregulation in mitochondria and beyond

The findings of this study suggest that toxic A peptides facilitate the oxidation of ascorbate through interactions with copper ions, leading to the production of hydroxyl radicals via the Fenton reaction (Valko et al., 2005[430]), the source of oxidative damage and neurotoxicity in the Alzheimer's disease brain