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If the dose threshold is reached at the beginning of the specified irradiation, then the subsequent responses are dose-independent (within a certain range)

If a pharmaceutical company will be supplying the drug, but will not itself be submitting the IND, the company is not the sponsor

2012 May 25;149 (5):1060-72

A study found that feeding rats EGCG before or after TBI prevented the production of free radicals, preventing neuronal degeneration and apoptotic death