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doi: 10.1038/nature11007

Long-term studies have measured cortisol levels in the hair of dogs

It possesses potent antioxidant and analgesic properties (Wilhelmsen 2011)

R 2 , R 3 , R 4 , and R 5 are independently selected from the group consisting of: H, C 1-4 alkyl, halogen-substituted C 1-4 alkyl, NR 9 R 10 , and CN