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Paclitaxel treatment promoted the anterograde transport of Na v 1.8 channels toward the distal axons, which resulted in an increased expression of Na v 1.8 channels at the surface of the distal axons from the cultured DRG neurons (Baker et al., 2023)

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Understanding obstacles to ethical global health research

In addition to these changes that result in decreased input from descending inhibitory pathways, mechanical changes to the muscle after SCI may also play a role in the pathophysiology of spasticity (13)