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Of enzymes that converts epoxyeicosatrienoic acids (EETs) to DHETs, the levels of microsomal epoxide hydrolase (EPHX1) positively correlated with fibrosis stage, but not soluble epoxide hydrolase (EPHX2)

Oxidative damage not repaired before DNA replication may cause cell death, DNA mutation, replication errors and genomic instability [7,8284]

AUTHOR CONTRIBUTIONS CB-V, BB-M, and OV performed conceptualization, methodology, formal analysis, writing the original draft, and funding acquisition

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