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Cell viability assay The cytotoxicity of MSCm, NanoSU6668, MNS, and T-MNS were determined using the Cell Counting Assay Kit-8 assay (40203ES76, Yeasen, Shanghai, China)

Meister M, Zhou J, Chu H, Coyne-Beasley T, Gahagan S, LaCoursiere D, Mueller E, Scal P, Simon L, Stapleton A, Stoll C, Sutcliffe S, Berry A, Wyman J, Consortium P, Brubaker L, Mueller E, Fitzgerald C, Hardacker C, Hebert-Beirne J, Lavender M, Shoham D, Markland A, Coyne-Beasley T, Burgio K, Lewis C, McGwin G, Vaughan C, Williams B, Lukacz E, Gahagan S, LaCoursiere D, Nodora J, Miller J, An L, Low L, Harlow B, Rudser K, Brady S, Chu H, Connett J, Fok C, Rockwood T, Constantine M, Newman D, Berry A, Epperson C, Schmitz K, Smith A, Stapleton A, Wyman J, Klusaritz H, Sutcliffe S, James A, Lowder J, Meister M, Rickey L, Camenga D , Lewis J, Cunningham S, Palmer M, Bavendam T

Your cells begin detoxifying

Consistent with this, we were able to increase the therapeutic dose by 2.5-fold without causing disproportionate stress or weight loss (Fig

These changes are summarized in Figure 1B