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The process begins with the hydrolysis of quercetin glycosides by lactase phloridzin hydrolase (LPH) and intracellular -Glucosidases and releases quercetin aglycone

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Western blotting of the bladder samples from the test group revealed lesser expression of NF-B and subsequent reduced production of Cox-2 and other proteins involved in inflammation, showing marked anti-inflammatory activity of lactone parthenolide in IC (Kiuchi et al., 2024)

This led to a rise in GSH turnover and a decrease in -glutamyl transpeptidase (-GT: GSH + amino acid + H 2 O) and 3L -glutamyl-amino acid (L-glutamate)