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Category 2 list expands to 19 peptides

Notably, the hypoxia-sensitive nature of lung tissue positions HIF-1 as a central regulator of amino acid metabolism

However, although these activated progenitors produce mature OLGs in the cuprizone model, the process fails in EAE, suggesting that inflammation (in EAE) may lead to an overactivation of GPR17, thereby preventing the terminal differentiation of OPCs (Coppolino et al., 2019)