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Histological analyses revealed that this reduction in adipose tissue size is associated with transformation of white adipose depots into a BAT-like appearance, with the formation of multilocular adipocytes, enlarged nuclei, and high UCP1 expression, a phenomenon known as browning that increases thermogenesis 27,28 (Fig

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Metabolomic analysis of alterations in lipid oxidation, carbohydrate and amino acid metabolism in dairy goats caused by exposure to Aflotoxin B1

Eleven healthy subjects were randomly assigned to either receive a coffee enema (3 times weekly for 6 visits) or consume ready-to-drink coffee (2 times daily for 11 days)

For calcium channel agonists experiments, WT and XKR8 KO neutrophils were loaded with Indo-1 and treated with probenecid (1 mM), GSK1016790A (100 nM), GSK1702934A (100 M), Yoda1 (10 M) or CBD (5 M)