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A systematic division of different strategies to target -syn thus separates stabilizing the physiological conformation of -syn, decreasing its expression, inhibiting its aggregation, and increasing intracellular clearance, from transmission-directed approaches including inhibiting uptake by neighboring cells and enhancing extracellular clearance mechanisms (Figure 2

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The roles of ferroptosis regulatory gene SLC7A11 in renal cell carcinoma: A multi-omics study

It has been suggested that loop diuretics might contribute to insulin resistance in the liver (Schliess et al., 2001) and as such contribute to increased hepatic gluconeogenesis, while thiazides may exacerbate insulin resistance in general (Ramsay et al., 1992