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10.1016/j.fct.2018.12.002 52 KimD

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In multiple clinical contexts, circulating markers such as cellfree DNA (dsDNA), myeloperoxidase (MPO)DNA complexes, and citrullinated histone H3 (CitH3) have been validated as indicators of NETosis and correlate with disease severity or activity in systemic inflammatory and thromboinflammatory disorders (e.g., cardiovascular disease, autoimmune conditions) [50, 66]

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Human NLRC4 expression promotes cancer survival and associates with type I interferon signaling and immune infiltration