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Cross-cancer comparisons reveal that although the SSP serves conserved functions in sustaining one-carbon unit supply and mediating therapeutic resistance across cancer types, the remarkable heterogeneity of its upstream regulatory mechanismsincluding Kras/FGFR3 mutations, MYC-mediated stemness maintenance, and m6A epigenetic modificationsdictates that therapeutic strategies must be precisely tailored

Decrease recovery time and enhance athletic performance

Impaired stress response and reduced anxiety in mice lacking a functional corticotropin-releasing hormone receptor 1

Low developmental competence and high tolerance to thermal stress of ovine oocytes in the warm compared with the cold season

Thus, IL-7, as a good factor, could selectively augment immune responses of the redirected CAR-T cells and/or intended effector cells