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Infected cells undergoing programmed apoptosis can enclose bacteria within apoptotic bodies, which are subsequently eliminated by efferocytosis through phagocytes, thereby reducing bacterial dissemination and long-term persistence (Vu et al., 2024)

A total of 445 articles were evaluated using their full texts, while 358 articles were removed due to factors such as untrustworthy study designs (including case reports, ethnographies, and observational designs), patient populations, interventions, outcome measurements, sample sizes smaller than 10, or the inaccessibility of the full text

CD4 CD4 is a critical protein of the adaptive immune system, which may be expressed on the surface of some lymphocytes, including T helper cells, monocytes, macrophages, and dendritic cells

Therefore, its deficiency can lead to clinical manifestations in the blood and nervous systems, affecting cell replication and fatty acid metabolism [49]

10.1016/s0301-0082(01)00003-x 23 BorstJ