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While Neupro delivers continuous dopaminergic stimulation, its use is limited by the need for daily application and possible local skin reactions (erythema and contact dermatitis) 136

The number of the conducted studies and the variety of applied approaches demonstrate the pronounced interest in developing suitable boron delivery agents

Even though some therapeutic options are in place, they fail to work effectively in the presence of diabetes as there are metabolic and molecular abnormalities that compromise their efficacy in diabetic conditions

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Erastin-induced ferroptosis has been closely associated with pathological ROS accumulation [13], and suppression of ROS generation can inhibit ferroptosis [40]