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[12] Healthcare providers will monitor any unusual responses and can adjust treatment if any potential interaction is suspected

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31 Since the 2021 review, one more RCT has been published that compared oral B12 alone, 25 g per day (form not reported), or with folate (800 g per day) versus no supplements for 6 months in patients with mild cognitive impairment

In a meta-analysis of randomized controlled trials, 2 g of myo-inositol administered orally twice daily was reported to be safe during pregnancy