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Additionally, an open-label, single arm pilot trial (OPTIMA) was designed to assess the efficacy and safety of inhaled GM-CSF (Molgramostim nebulized solution) in treating NTM-PD in adults with non-CF bronchiectasis ( Although these data have not fully demonstrated the exact efficacy of NE inhibitors in the treatment of bronchiectasis, researchers continue to explore and optimize the therapeutic strategies for NE inhibitors, including the development of inhaled NE inhibitors to increase the concentration of the drug in the lungs and thus improve the clinical efficacy

10.1016/s0002-9394(99)00103-8 Am

Immunity 55 (8), 13701385.e8

Pilarski R, Burt R, Kohlman W, et al.: Cowden syndrome and the PTEN hamartoma tumor syndrome: systematic review and revised diagnostic criteria

Int J Biochem 24(7):10471050 Romero-Moraleda B, Peinado Lozano AB, Morencos Martinez E, Lopez-Plaza B, Gomez Candela C, Calderon Montero FJ et al (2015) Lipid profile response to weight loss program in overweight and obese patient is related with gender and age