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This review discusses the role of oxidative stress in mediating separate pathological events that together, ultimately result in cell death in PD

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SOD catalyzes the dismutation of superoxide anions (O2-) into oxygen (O2) and hydrogen peroxide (H2O2)

doi: 10.4103/1673-5374.306082, 18

1,2 Undoubtedly, a fundamental challenge is deciphering how proteostasis is ensured in cellular organelles

Discovery of 2-[3,5-dichloro-4-(5-isopropyl-6-oxo-1,6-dihydropyridazin-3-yloxy)phenyl]-3,5-dioxo-2,3,4,5-tetrahydro[1,2,4]triazine-6-carbonitrile (MGL-3196), a highly selective thyroid hormone receptor agonist in clinical trials for the treatment of dyslipidemia