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doi: 10.2147/ijwh.s4730

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The consumption of a high-fat or high-cholesterol diet can result in dyslipidaemia in RA patients, notably increasing total cholesterol (TC) and low-density lipoprotein (LDL) levels while decreasing high-density lipoprotein (HDL) levels [44]

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Loss of SAMe-mediated transsulfuration depletes brain glutathione levels, impairing cerebral antioxidant activity and perpetuating neuroinflammation

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