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37,38 Though PTGS2 did not show the different expression in ScRNA-seq of pulpitis vs healthy pulp, immunochemistry assay showed that PTGS2 high expressed in pulpitis

One of the most common mechanisms of drug resistance is enhanced drug detoxification mediated by detoxifying enzymes such as glutathione S-transferases (GSTs), which can be exploited by malignant cells to increase survival through the acquisition of resistance to anticancer drugs (Coles and Ketterer 1990

Notably, knockdown of FOXO1 has been shown to increase the number of dopaminergic neurons in cerebral organoids derived from GBA-PD models (Zagare et al

doi: 10.1016/j.braindev.2008.12.017 67 MinichW

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