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Mitochondrial DNA in Innate Immune Responses and Inflammatory Pathology

Doxy further impairs mitochondrial function, increasing ROS generation and enhancing PDT to promote more effective tumor cell destruction and stronger ICD Doxy inhibits autophagy to increase MHC-I expression on tumor cell surfaces, hence enhancing antigen presentation and cytotoxic T lymphocyte (CTL) identification, which improves tumor immunogenicity