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Cell Rep (2019) 28(10):265972.e6

PMID: 25927528

moreover, it has become common practice to also immunopurify samples for the Initial Testing Procedure

These phosphorylated Smad2 and Smad3 then interact with their co-chaperone Smad4 to form a complex that reaches the nucleus and stimulates the transcription of pro-fibrotic genes[48]