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NaunynSchmiedebergs Arch Pharmacol 384(2):157167 Isacson O, Brundin P, Gage FH, Bjrklund A (1985) Neural grafting in a rat model of Huntingtons disease: progressive neurochemical changes after neostriatal ibotenate lesions and striatal tissue grafting

168 Renin, which is secreted by juxtaglomerular cells that sense hypoperfusion, catalyzes angiotensin II synthesis, inducing afferent arteriolar vasoconstriction, increasing systemic blood pressure, and promoting sodiumwater retention via aldosterone

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In detail, when combined with RT, shrinkage was observed in 9 out of 13 and only 1 out of 17 individual tumor nodules in the LDHB knockout versus wild-type background, respectively (Fig