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7,14,15 Although HS was traditionally viewed as a disease of the sweat glands, current understanding suggests it is a disorder of the follicular epithelium resulting from repetitive mechanical stress in genetically susceptible individuals

It's closer to 20% effective, and that remaining 20% drops to near-zero by week four

This is consistent with the phase 2b clinical trial, where the total 12-week result was 2.8kg (6.2 lbs) additional fat loss versus placebo (clinical trial data)

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The pharmaceutical formulation disclosed herein may comprise hydroxypropyl-beta-cyclodextrin having about 0.6-0.9 hydroxypropyls per glucose unit