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While immune cell activation and cytokine production have a minor impact on the CNS during physiological perturbations, chronic systemic inflammation, mainly in the form of infections, has long been associated with behavioral alterations and cognitive dysfunction (264266)

Moreover, dosing acid to lower pH, ammonia, excessive H 2 O 2 and OH scavenger to water may reduce BrO 3 - production [ 69 ] as well

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PMID 19773279

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