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Cytokine stormthe deadly systemic inflammation The hyperinflammatory state with the elevated cytokine levels [19], CSS, results in an overwhelming systemic inflammation to exacerbate viral pathogenesis, sepsis, acute respiratory distress syndrome (ARDS), and multi-organ failure/damage [35]

Tissue homogenates were centrifuged at 8000 x g for 10 min at 4 C, and supernatant was collected and re-centrifuged using the same conditions

The UPLC mobile phase consisted of a linear gradient of the two mixtures of 0.1% TFA in water and 0.1% TFA in acetonitrile (ACN)

Zhang et al., 2005)